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Specialty Fetal Bovine Serum

Serum Source International offers an extensive range of specialty types of Fetal Bovine Serum to meet any serum requirement for your specific cell culture application, satisfying the needs of research as well as industrial use.  Many investigational studies require that certain components in Fetal Bovine Serum be removed, further reduced or inactivated to ensure no interference within the specific research study.  Special treatments or further processing set to the highest Industry Standards can be performed to improve the safety levels of possible contamination for industrial use.  Furthermore, Serum Source International offers a wide selection of pre-tested types (selected lots) of Fetal Bovine Serum that are chosen to be specifically suitable for particular applications due to the natural characteristics, proving optimal performance results with certain cell lines. 

Heat Inactivated, Fetal Bovine Serum:

All Fetal Bovine Serum products are available heat inactivated and must be specified at the time of placing your order. Fetal Bovine Serum is heat inactivated in controlled conditions at 56° C for 30 minutes, intended to inactivate undesirable serum complement.

Heat inactivating serum is ideal for immunoassays and certain enzyme tests. It is also suitable when used in cell culture as a culture medium additive, a stabilizer or for coating culture vessels.

Please click here for our detailed heat inactivation instructions.

Product Catalog # Size
USA Origin FB02-100HI 100 mL
USA Origin FB02-500HI 500 mL
USDA Approved Origin FB22-100HI 100 mL
USDA Approved Origin FB22-500HI 500 mL
Australia Origin FB33-100HI 100 mL
Australia Origin FB33-500HI 500 mL

Gamma Irradiated, Fetal Bovine Serum:

Sterile filtration can ensure that Fetal Bovine Serum is almost entirely free of micro-organisms, but gamma irradiation will further reduce or eliminate the range of viruses and mycoplasmas which may be present after filtration. Gamma Irradiated Fetal Bovine Serum is suitable for the most stringent sterility requirements set in the Industry, such as virus and vaccine production, biopharmaceutical production processes and the production of diagnostic products.

Gamma Irradiated Fetal Bovine Serum is exposed to ionizing radiation at a dose between a minimum of 25 kGy and a maximum of 40 kGy. The serum will be gamma irradiated in small packages on a conveyor past the radiation source, ensuring the sensitive growth factors are protected as much as possible and the serum remains homogeneous.
Product Catalog # Size
USA Origin FB02-100GI 100 mL
USA Origin FB02-500GI 500 mL
USDA Approved Origin FB22-100GI 100 mL
UDSA Approved Origin FB22-500GI 500 mL
Australia Origin FB33-100GI 100 mL
Australia Origin FB33-500GI 500 mL

Dialyzed, Fetal Bovine Serum:

Dialyzed Fetal Bovine Serum is used in applications requiring serum that has been highly reduced or depleted of small molecules, such as nucleotides, hormones, salts, proteins and amino acids weighing less than 10 kDa that could interfere with certain investigational studies. This process involves dialyzing the serum against physiological saline through a 10,000 Dalton cut-off membrane, involving a careful approach in controlled conditions, while monitoring the glucose concentration level throughout the duration. Dialyzed Fetal Bovine Serum is suitable to use as an additive for cell culture media and is thought to be ideal when used in incorporation or receptor studies.
Product Catalog # Size
USA Origin FB02-100DI 100 mL
USA Origin FB02-500DI 500 mL
USDA Approved Origin FB22-100DI 100 mL
USDA Approved Origin FB22-500DI 500 mL
Australia Origin FB33-100DI 100 mL
Australia Origin FB33-500DI 500 mL

Tetracycline Negative, Fetal Bovine Serum:

Tetracycline Negative Fetal Bovine Serum contains a maximum level of 5 µg/ml tetracycline or tetracycline derivative concentration. The tetracycline level is measured using an ELISA kit system. This serum is ideal for expression studies with Tet-on / Tet-off systems, as the presence of tetracycline could interfere with tetracycline regulated gene expression systems. Tetracycline negative serum contains low endotoxin and IgG levels.
Product Catalog # Size
USA Origin FB02-100TET 100 mL
USA Origin FB02-500TET 500 mL
USDA Approved Origin FB22-100TET 100 mL
USDA Approved Origin FB22-500TET 500 mL
Australia Origin FB33-100TET 100 mL
Australia Origin FB33-500TET 500 mL

Charcoal Stripped, Fetal Bovine Serum:

Charcoal Stripped Fetal Bovine Serum is filtered through charcoal, involving a process to strongly reduce the levels of hormones and steroids. This type of serum is primarily used in applications that require low levels of certain hormones or steroids such as progesterone, cortisol, corticosterone, testosterone, triiodothyronine (T3), thyroxine (T4), estradiol and insulin, reducing the possibility of interference within applicable research studies. Sometimes, important growth factors and cytokines are also eliminated during this process which could result in a possible suppressed cell differentiation. This serum is ideal when used in hormone reduction cell culture, receptor studies and research in regards to steroid hormones in vitro.
Product Catalog # Size
USA Origin FB02-100CS 100 mL
USA Origin FB02-500CS 500 mL
USDA Approved Origin FB22-100CS 100 mL
USDA Approved Origin FB22-500CS 500 mL
Australia Origin FB33-100CS 100 mL
Australia Origin FB33-500CS 500 mL

IgG Stripped, Fetal Bovine Serum:

The IgG level is reduced to below 5 µg/ml in IgG Stripped Fetal Bovine Serum by hydrophobic charge induction chromatography (HCIC), making this type of serum ideal for hybridoma cell culture and the production of monoclonal antibodies. It is also suitable when used as an additive for cell culture media.
Product Catalog # Size
USA Origin FB02-100IgG 100 mL
USA Origin FB02-500IgG 500 mL
USDA Approved Origin FB22-100IgG 100 mL
USDA Approved Origin FB22-500IgG 500 mL
Australia Origin FB33-100IgG 100 mL
Australia Origin FB33-500IgG 500 mL

Embryonic Stem (ES) Cell Pre-tested, Fetal Bovine Serum:

Embryonic Stem (ES) Cell Pre-tested Fetal Bovine Serum eliminates the need to test the serum prior to using it with embryonic stem cells or amnion and chorionic villi cells in cytogenetics. This serum undergoes pre-testing by one of our experienced ES cell culturists, proving the ability to support the growth of undifferentiated colonies of ES cells. ES screened Fetal Bovine Serum is selected after studying the morphology of the stem cell colonies, plating efficiency and cytotoxicity assays. It is ideal for many types of primary cells.
Product Catalog # Size
USA Origin FB02-100ES 100 mL
USA Origin FB02-500ES 500 mL
USDA Approved Origin FB22-100ES 100 mL
USDA Approved Origin FB22-500ES 500 mL
Australia Origin FB33-100ES 100 mL
Australia Origin FB33-500ES 500 mL


Intended Use: For research and further manufacturing use only. Not intended for human or therapeutic use.

Safety: Please click to review our Material Safety Data Sheet (MSDS) for Fetal Bovine Serum.

Storage: Temperature -20°C

Shipping Method: Frozen on dry Ice

Please note that all types of serum may not be available in your requested origin. Contact a Sales Representative for current availability. Prices are subject to change without notice.